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Zhimin Feng

Senior Instructor
Biological Sciences
Case School of Dental Medicine
United States of America

Professor Biochemistry
Biography

PhD, Cell Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China MS, Medical Biochemistry, School of Medicine, Southeast University, Nanjing, China BS, Biochemistry, Nanjing University, Nanjing, China

Research Intrest

Research Summary: Dr. Feng's research area is epithelial innate immunity. He is working on the regulation and function of human beta-defensins (hBDs), structure/function analysis of hBD-3 and CXCR4 interactions, as well as epithelial innate immune responses to microbial challenges. Research Keywords: Innate immunity, Human beta defensins (hBDs), Epithelial biology, Microbial challenge

List of Publications
Z Feng, Aaron Weinberg. Role of bacteria in health and disease of periodontal tissues. Periodontology 2000, 40: 50-76, 2006.
ME Quinones-Mateu, MM Lederman, Z Feng, B Chakraborty, J Weber, HR Rangel, ML Marotta, M Mirza, B Jiang, P Kiser, K Medvik, SF Sieg and A Weinberg. Human epithelial β-defensins 2 and 3 inhibit HIV-1 replication. AIDS, 17:F39 -F48, 2003
Nicholas Funderburg, Michael M. Lederman, Zhimin Feng, Michael G. Drage, Julie Jadlowsky, Clifford V. Harding, Aaron Weinberg, and Scott F. Sieg. Human β defensin-3 activates professional antigen-presenting cells via Toll like Receptors 1 and 2. Proc. Nat. Acad. Sci, 104: 18631-18635, 2007.
Z Feng, J Chandra, M Ghannoum, A Weinberg. Human beta-defensin activity against candida. J Dent Res, 84: 445-450, 2005.
Zhimin Feng, George R. Dubyak, Michael M. Lederman, Aaron Weinberg. Cutting Edge: Human beta defensin 3─A novel antagonist of the HIV-1 co-receptor CXCR4. J. Immunol, 177: 782-786, 2006.

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