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Zbigniew Wróbel

Associated Professor
Target synthesis
Institute of Organic Chemistry, Polish Academy of Sciences
Poland

Professor Molecular Biology
Biography

Zbigniew Wróbel is Associated Professor, is currently work in the Institute of Organic Chemistry, Polish Academy of Sciences as a Head of the group of Target synthesis

Research Intrest

Synthesis of heterocyclic nitrogen compounds including mainly quinolines and indoles starting from aromatic nitrocompounds. Synthesis of N-aryl-2-nitrosoanilines from anilines and aromatic nitrocompounds and their use as substrates in formation of more compicated nitrogen heterocycles like benzimidazoles, quinoxalines or phenazines Investigation of transformation of σH adducts into nitroso compounds. The group offers also services in the field of: - common organic synthesis - peptide synthesis

List of Publications
Zbigniew Wróbel, Krzysztof Wojciechowski “Synthesis of Substituted 3-Cyano and 3-(Arenesulfonyl)indoles from o-Nitrobenzyl Cyanides and Sulfones” Synlett2011, 2567 –71.
Zbigniew Wróbel, Karolina Stachowska, Krzysztof Grudzień, Andrzej Kwast “N-Aryl-2-nitrosoanilines in the Two-Step Sythesis of Substituted 1,2-Diarylbenzimidazoles from simple Nitroarenes” Synlett2011,1439 – 1443.
Zbigniew Wróbel, Andrzej Kwast, “Simple Synthesis of N-Aryl-2-nitrosoanilines in the Reaction of Nitroareneswith Aniline Anion Derivatives” Synthesis 2010, 3865.
Zbigniew Wróbel, Krzysztof Wojciechowski, Andrzej Kwast, Norbert Gajda “Short and Simple Method of Synthesis of Some Pyrrolo[3,2-b]quinoline Derivatives from Easily Available Nitrobenzene Derivatives” Synlett 2010, 2435.
Robert Bujok, Andrzej Kwast, PiotrC moch, Zbigniew Wróbel “Novel approach to synthesis of substituted 3-aminoquinolines from nitroarenes and protected ethyl aminocrotonate” Tetrahedron 2010, 66, 698–708.
Bobin, M.; Kwast, A.; Wróbel, Z. „Efficient formation of σH-adducts as a key step in the synthesis of acridines via Lewis acid promoted transformations of the nitro group” Tetrahedron 2007, 63, 11048-11054.
Wróbel, Z.; Kwast, A. „2-Nitroso-N-arylanilines: Producs of Acid –Promoted Transformation of σH Adducts of Arylamines and Nitroarenes” Synlett, 2007, 1525-1528.
Wróbel, Z.; Kwast, A. „Nucleophilic Substitution of Halogens with Amines in 2- and 4-Nitrophenols” Synthesis 2007, 259-262.
Experts in Poland
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