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You Han Bae

Professor
Pharmaceutics and Pharmaceutical Chemistry
Huntsman Cancer Institute
United States of America

Professor Pharmaceutical Sciences
Biography

You Han Bae, PhD, is a Professor in the Department of Pharmaceutics & Pharmaceutical Chemistry and an Adjunct Professor in the Department of Bioengineering at the University of Utah. He is an investigator of the Huntsman Cancer Institute and a member of the Experimental Therapeutics Program.Dr. Bae’s research interests include selective targeting of drugs to acidic extracellular environments, which often surround cancer cells. His lab also studies self-assembled super pH-sensitive nanoparticles as a potential drug delivery system for treating cancers which are multidrug resistant. He is also interested in developing delivery systems for protein biologics, as well as improved gene delivery systems.Bae received a PhD from and completed postdoctoral training at the University of Utah.

Research Intrest

Protein drug stabilization and controlled release Polymeric systems for rechargeable cell delivery Self-assembled super intelligent nanoparticulates for sensitive and resistant tumor targeting

List of Publications
Nichols JW, Bae YH (2012). Odyssey of a cancer nanoparticle: from injection site to site of action. Nano Today, 7(6), 606-618.
Lee YJ, Kang HC, Hu J, Nichols JW, Jeon YS, Bae YH (2012). pH-Sensitive polymeric micelle-based pH probe for detecting and imaging acidic biological environments. Biomacromolecules, 13(9), 2945-51.
Hu J, Miura S, Na K, Bae YH (2013). pH-responsive and charge shielded cationic micelle of poly(l-histidine)-block-short branched PEI for acidic cancer treatment. J Control Release, 172(1), 69-76.
Yim H, Park SJ, Bae YH, Na K (2013). Biodegradable cationic nanoparticles loaded with an anticancer drug for deep penetration of heterogeneous tumours. Biomaterials, 34(31), 7674-82.
Kim KS, Park W, Hu J, Bae YH, Na K (2014). A cancer-recognizable MRI contrast agents using pH-responsive polymeric micelle. Biomaterials, 35(1), 337-43.

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