As an Professor Wu Zhuanyue th internationally renowned fine cells raw biologists, pioneering work done a lot of biological signal transduction, cell adhesion, formation and regulation of the extracellular matrix, which is a human research for cell adhesion and extracellular matrix formation The mechanism to understand one of the milestones has created a theory of extracellular matrix formation by cell surface receptors. Recent studies have confirmed that this theory for a variety of extracellular matrix formation and information transmission has a guiding significance for the adhesion and metastasis of tumor cells is important. The series of research results in the "cell", "cell biology", "molecular cells", "natural structural biology" and other world-class academic journals published in this area of ​​research had a profound impact. As a leading scientist with international influence in this field, Professor Wu Chuanyue has been invited to report or preside over the symposium at major international academic conferences (including the Gordon Research Conference) and was invited to the Journal of Cell Biology, " Current Opinion in Cell Biology " , " Trends in Cell Biology " , " EMBO Reports " and other major international academic journals published articles and as a number of international academic magazine editorial board and the US National Institutes of Health, the American Cancer Research Association of scientific research Fund, the Canadian Cancer Research Association Scientific Research Fund, the British Wellcome Fund and other institutions of the judges and the National Natural Science Foundation of China key project second instance experts (Medical Science Department).

1)Integrin signaling pathway and regulation; 2)the mechanism and mechanism of cell microenvironment and cell interaction in mechanical force signal transduction; 3)the role of cell matrix on stem cell renewal, differentiation, migration and so on and its role in organ development, injury repair and mechanism; 4)cell microenvironment and cell interactions in human major diseases (including cancer, kidney failure and bone Joint disease, etc.) in the development and development of the role.