William Ramses Bishai

Professor
Medicine - Infectious Diseases
Johns Hopkins University
United States of America

Biography

Dr. William Bishai is a professor of medicine at the Johns Hopkins University School of Medicine. He holds joint appointments in pathology and in molecular biology and genetics and, at the Johns Hopkins Bloomberg School of Public Health, in international health. His area of clinical expertise is infectious diseases. Dr. Bishai serves as co-director of the Johns Hopkins Center for Tuberculosis Research. Dr. Bishai received his B.A. from Harvard University and an M.Phil. from Cambridge University. He earned his M.D. and Ph.D. from Harvard and completed his residency at the Brigham and Women’s Hospital. He performed his fellowship in infectious diseases at Johns Hopkins. Dr. Bishai was a Howard Hughes postdoctoral research fellow before he joined the Johns Hopkins faculty in 1994.

Research Intrest

Molecular biology of mycobacterium tuberculosis.

List of Publications
Winglee K, Lun S, Pieroni M, Kozikowski A, Bishai W. "Mutation of Rv2887, a marR-like gene, confers Mycobacterium tuberculosis resistance to an imidazopyridine-based agent." Antimicrob Agents Chemother. 2015 Nov;59(11):6873-81.
Maiga MC, Ahidjo BA, Maiga M, Bishai WR. "Roflumilast, a Type 4 phosphodiesterase inhibitor, shows promising adjunctive, host-directed therapeutic activity in a mouse model of tuberculosis." Antimicrob Agents Chemother. 2015;59(12):7888-7890.
Silva JR, Bishai WR, Govender T, Lamichhane G, Maguire GE, Kruger HG, Lameira J, Alves CN. "Targeting the cell wall of Mycobacterium tuberculosis: a molecular modeling investigation of the interaction of imipenem and meropenem with L,D-transpeptidase 2." J Biomol Struct Dyn. 2016 Feb;34(2):304-17.