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Experts in Pathology
Dr. Sajjan Singh Surana Mahua Choudhury Joseph C. Gregorek Mireya correa Cory Abate-Shen Rosanna G. Abellar Abdul Samad Dr. Ahmed MagdyMetwallyAbd Al Hamid Ester Ballana Guix Jianguo (Jeff) Xia Jen Ronholm David Murdoch Peter D Canoll Susan Best Ryan Blaedow Sofia Avnet Lucio Montanaro Lynn K Carta Kurian P. Abraham Dr Gavin Hunter View MoreWilliam A Muller
Professor
Department of Pathology
Northwestern University Feinberg School of Medicine
United States of America
PhD: Rockefeller U (1981) MD: Cornell U Medical Ca (1982) Internship: Massachusetts General Hospital (1983) Residency: Brigham & Women's Hospital (1987) Board Certification: Anatomic Pathology
His lab studies the inflammatory response at the cellular and molecular level. they are focused on the process of diapedesis, the "point of no return" in inflammation where leukocytes squeeze between tightly apposed endothelial cells to enter the site of inflammation. We have identified and cloned several molecules that are critical to the process of diapedesis (PECAM (CD31), CD99, and VE-cadherin) and are studying how they regulate the inflammatory response using in vitro and in vivo models. they have recently described the Lateral Border Recycling Compartment, a novel para-junctional organelle that contains PECAM and CD99 and is critical for diapedesis to occur. they are currently investigating how this compartment regulates diapedesis in the hope of finding novel targets for anti-inflammatory therapy.