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Toshiyuki Sakai

Department of Health Sciences and Preventive Medicine
Kyoto Prefectural University of Medicine
Japan

Professor Healthcare
Biography

Dr. Toshiyuki Sakai is working as Professor in Kyoto Prefectural University of Medicine. His research has included chemotherapy of cancer, novel anti-cancer drugs and cancer preventive foods. He have authored 5 research articles.

Research Intrest

 chemotherapy of cancer, novel anti-cancer drugs and cancer preventive foods

List of Publications
Nakano K, Mizuno T, Sowa Y, Orita T, Yoshino T, Okuyama Y, Fujita T, Ohtani-Fujita N, Matsukawa Y, Tokino T, Yamagishi H, Oka T, Nomura H, Sakai T. Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line.The Journal of Biological Chemistry. 1997 Aug 29;272(35):22199-206.
Yoshida T, Shiraishi T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T. Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein. Cancer Research. 2005 Jul 1;65(13):5662-7.
Shiraishi T, Yoshida T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T. Tunicamycin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human prostate cancer cells. Cancer Research. 2005 Jul 15;65(14):6364-70.
Shii N, Harada N, Joseph EW, Ohara K, Miura T, Sakamoto H, Matsuda Y, Tomii Y, Tachibana-Kondo Y, Iikura H, Aoki T, Shimma N, Arisawa M, Sowa Y, Poulikakos PI, Rosen N, Aoki Y, Sakai T. Enhanced inhibition of ERK signaling by a novel allosteric MEK inhibitor, CH5126766, that suppresses feedback reactivation of RAF activity. Cancer Research. 2013 Jul 1;73(13):4050-4060.
Experts in Japan
Takeshi Kikuchi GOTOH Tetsuo OHTA Hiroyuki MIYAGAWA Happei Isamu Nishida ABE Takashi AIHARA Hiroaki AKAGI Yutaka AKASHI Ryosuke AKIYAMA Ryota ANDO Masaki ASAI Shoji BAMBA Aya ENOKI Sawako FUJIMORI Atsushi FUKUYAMA Hiroshi FURUKAWA Shunsuke FUKUSHIMA Kenji HAMAGUCHI Koichi HASEGAWA Shuji HAYASHI Masamitsu HIGUCHI Hideo SAKAKI Makoto HIRAIWA Tetsuya TAMBARA DAISUKE View More