Tibor Kovacsovics

Professor
Department of Hematology
Huntsman Cancer Institute
United States of America

Professor Haematology
Biography

Dr. Kovacsovics graduated from the University of Geneva Medical School, and was a Resident in Internal Medicine at the Clinique Médicale Thérapeutique at Geneva University Hospital, Switzerland, after which he became Chief Resident at the same institution. He also completed training as a Research Assistant at the Institute of Biochemistry at the University of Lausanne, Switzerland. He then became a Clinical and Research Fellow in Medicine, Hematology-Oncology, at Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard Medical School. This was followed by positions as “Chef de Clinique” and “Médecin Associé” in the Division of Hematology at Lausanne University Hospital, Switzerland, where he set up the autologous hematopoietic stem cell transplant program. In 2004 he was recruited to the Faculty at Oregon Health Science University, where he developed a program in acute leukemia, with a focus on innovative clinical trials and molecular diagnostics. Dr. Kovacsovics has served as both principal investigator and co-investigator on numerous clinical trials and grants. Many of his clinical trials focus on new agents for treatment of acute leukemias. He is a member of multiple professional societies, and was the chairman of the Swiss Leukemia Cooperative Group (SAKK) from 2002-2004. He has published over forty peer-reviewed manuscripts, and is a regular reviewer for many top Hematology journals, including Blood, American Journal of Cancer, Haematologica, and Leukemia.

Research Intrest

Acute Myeloid Leukemia (AML) Acute Lymphoblastic Leukemia Chemotherapy Hematopoietic Stem Cell Transplantation

List of Publications
Claxton D, Erba HP, Faderl S, Arellano M, Lyons RM, Kovacsovics T, Gabrilove J, Huebner D, Gandhi PJ, Kantarjian H (2012). Outpatient consolidation treatment with clofarabine in a phase 2 study of older adult patients with previously untreated acute myelogenous leukemia. Leuk Lymphoma, 53(3), 435-40.
Tyner JW, Yang WF, Bankhead A 3rd, Fan G, Fletcher LB, Bryant J, Glover JM, Chang BH, Spurgeon SE, Fleming WH, Kovacsovics T, Gotlib JR, Oh ST, Deininger MW, Zwaan CM, Den Boer ML, van den Heuvel-Eibrink MM, OHare T, Druker BJ, Loriaux MM (2013). Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening. Cancer Res, 73(1), 285-96.
Scott EC, Heitner SB, Dibb W, Meyers G, Smith SD, Abar F, Kovacsovics T, Perez-Avraham G, Stentz A, Frires R, Dibb J, Maziarz RT (2014). Induction bortezomib in Al amyloidosis followed by high dose melphalan and autologous stem cell transplantation: a single institution retrospective study. Clin Lymphoma Myeloma Leuk, 14(5), 424-430.e1.
Cogle CR, Goldman DC, Madlambayan GJ, Leon RP, Al Masri A, Clark HA, Asbaghi SA, Tyner JW, Dunlap J, Fan G, Kovacsovics T, Liu Q, Meacham A, Hamlin KL, Hromas RA, Scott EW, Fleming WH (2014). Functional integration of acute myeloid leukemia into the vascular niche. Leukemia, 28(10), 1978-87.
Lancet JE, Cortes JE, Hogge DE, Tallman MS, Kovacsovics TJ, Damon LE, Komrokji R, Solomon SR, Kolitz JE, Cooper M, Yeager AM, Louie AC, Feldman EJ (2014). Phase II, multicenter, randomized, open label trial of CPX-351 (cytarabine:daunorubicin) liposome injection versus cytarabine and daunorubicin in patients with untreated AML 60-75 years of age. Blood.