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Krishna Sundari Kenneth C. Carroll Roy D. Welch Ratan Gachhui Lacy Daniels Hardik Pathak Varsha Gupta Smriti Gaur Alok Kalra Franklin, Portugal Mohammad Hayatul Islam Professor Clive Ronson Anthony Garza Joseph Ashour Evelyn de Souza Oliveira Lopes Alexander Borisovich Prikhodko Prof. M.S. Dkhar Prof. H. Kayang Rizwana Rahim Dr. Papiya Ramanujam View More
Thomas Rudel

Dean
Department of Biology and microbiology
The Julius Maximilian University of Wurzburg
Germany

Professor Microbiology
Biography

Academic Career 1983-1989: Studies of Biology, University of Tübingen 1989-1994: PhD in Microbiology, Max Planck Institute for Biology, Tübingen 1994-1995: Staff scientist, Max Planck Institute for Biology, Tübingen 1995-1996: Postdoctoral fellow, Scripps Research Institute, San Diego, USA 1997-2008: Group leader, Max Planck Institute for Infection Biology, Berlin 2001: Habilitation (Microbiology), Free University Berlin 2003: associate professor, Max Planck Institute for Infection Biology, Berlin Since 2008: Chair Professor, Chair of Microbiology, University of Würzburg

Research Intrest

Research projects: Chlamydia infection - a risk factor for ovarian and cervical carcinoma? The tumor metabolism as an attack point for a therapy The intracellular niche of Chlamydia Cellular inherent and innate immune defense Mechanism of disseminated gonococcal infection RNA as a regulator in gonococcal infection Metabolic interactions between chlamydia and the host cell Sphingolipids in gonococcal infection The host cell death induced by Staphylococcus aureus

List of Publications
Eisenreich W, Rudel T , Heesemann J Goebel W. To Eat and Be Eaten to: Mutual Metabolic Adaptations of Immune Cells and Intracellular Bacterial Pathogens upon infection. Front Cell Infect Microbiol. 2017 Jul 13, 7: 316. Doi: 10.3389 / fcimb.2017.00316 . Chowdhury SR, Rudel T . Chlamydia and mitochondria - an unfragmented relationship. Microb Cell. 2017 Jun 14, 4 (7): 233-235. Doi: 10.15698 / mic2017.07.582. Tanwer P, Bauer S, Henry E, Panda G, D Saluja, Rudel T , Beier D. Post-transcriptional regulation of target genes by the sRNA FNRS in Neisseria gonorrhoeae. Microbiology. 2017 Jul, 163 (7): 1081-1092. Doi: 10.1099 / mic.0.000484. Fischer A, Harrison KS, Ramirez Y, D Auer, Chowdhury SR, Prusty BK, Sauer R, Z Dimond, Kisker C, Scott Hefty P, Rudel T. Chlamydia trachomatis -containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to Interfere with host defense. Elife. 2017 Mar 28; Pii: e21465. Doi: 10.7554 / eLife.21465 . Gupta N, Noel R, Goudet A, Hinsinger K, Michau A, Pons V, Abdelkafi H, Secher T, Shima A, Shtanko O, Sakurai Y, Cojean S, Pomel S, Lievin-Le Moal V, Leignel V, Herweg JA , Fischer A, Johannes L, Harrison K, Beard PM, Clayette P, Le Grand R, Rayner JO, Rudel T , Vacus J, Loiseau PM, Davey RA, Oswald E, Cintrat JC, Barbier J, Gillet D. Inhibitors of retrograde Trafficking active against ricin and Shiga toxins, so protect cells from several viruses, Leishmania and Chlamydiales. Chem Biol Interact. 2017 Apr 1, 267: 96-103 doi: 10.1016 / j.cbi.2016.10.005 PMID: 27712998 Mehlitz A, Eylert E, Huber C, Lindner B, Vollmuth N, K Karunakaran, Goebel W, W Eisenreich, Rudel T . Metabolic adaptation of Chlamydia trachomatis to mammalian host cells. Mol Microbiol. 2017 Mar 103 (6): 1004-1019. Doi: 10.1111 / mmi.13603 PMID: 27997721 Chowdhury SR, Reimer A, M Sharan, Kozjak Pavlovic V, Eulalio A, BK Prusty, Frauenholz M, K Karunakaran, Rudel T . Chlamydia preserves the mitochondrial network necessary for replication via microRNA-dependent inhibition of fission. J Cell Biol. 2017 Mar 22. pii: jcb.201608063. Doi: 10.1083 / jcb.201608063 PMID: 28330939 Reimer A, F Seufert, Weiwad M, J Ebert, Bzdyl NM, Bare CM, Sarkar Tyson M, wooden tomb U, Rudel T , Kozjak Pavlovic V. inhibitor of macrophage infectivity potentiator-like PPIases affect neisserial and chlamydial pathogenicity. Int J Antimicrob Agents. 2016 Oct 48 (4): 401-8. Doi: 10.1016 / j.ijantimicag.2016.06.020 PMID: 27516227 A, B, C, T, C, T, T , T , T , T , Fraunholz MJ. Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival in Epithelial Cells and Phagocytes. PLoS Pathog. 2016 Sep 15, 12 (9): e1005857 doi: 10.1371 / journal.ppat.1005857 "PMID: 27632173; PMCID: PMC5025175" Fischer A, Rudel T . Subversion of Cell-Autonomous Host Defense by Chlamydia Infection. Curr Top Microbiol Immunol. 2016 May 13. PMID: 27169422 The S, Lindemann C, Young BC, Muller J, Austria B, Ternette N, Winkler AC, Paprotka K, Reinhardt R, Förstner KU, Allen E, Flaxman A, Yamaguchi Y, Rollier CS, van Diemen P, Blättner S, Remmele CW, Selle M, Dittrich M, Müller T, Bird J, Ohlsen K, Crook DW, Massey R, Wilson DJ, Rudel T , Wyllie DH, Fraunholz MJ. Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation. Proc Natl Acad Sci US A. 2016 May 31; 113 (22): E3101-10 doi: 10.1073 / pnas.1520255113 "PMID: 27185949; PMCID: PMC4896717"
Experts in Germany
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