My research interests focus on the long term effects of chronic lung disease on respiratory structure and resultant lung function. Lab research involves measuring structural function with serial CT imaging at similar lung volumes and expiratory CT scans to optimize evaluation of regional small airway disease. The advantage of understanding the molecular and physiologic events of lung disease provides the opportunity for preemptive medical intervention before symptoms appear.

My research interests focus on detection of early and progressive Cystic fibrosis (CF) structural lung disease by utilizing chest CT imaging and CT post-processing methodology. Current research efforts involve utilization of low dose infant & children CT imaging protocols and quantitative airway and air trapping algorithms to evaluate early and progressive CF disease. Additional areas of research in our laboratory include defining more direct pulmonary outcome measures to evaluate treatment effects in chronic diseases such as cystic fibrosis and pulmonary alveolar proteinosis.