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Experts in Neurology
Eun-Young Lee Shahdat Hossain NITIN M. NAGARKAR Kevin A Roth Asa Abeliovich Dritan Agalliu Ottavio Arancio Edmund Au Francesca Bartolini Wu Anhua  Priti Balchandani Prof. Dr. Raghda Nasr Ibrahim Nasr Nassa Jacque Dalton Sara Johnston Dr. Ryoko Sasamoto Evans Spears Zachery Sneed Nadine Bakkar Dave Schroeder Jennifer Basil View MoreSwananda Marathe
Inspire faculty fellow
Department of Neuroscience
Indian Institute of Science
India
Although how neurons influence behavior has been investigated in great detail, there has been little clarity on the role played by astrocytes, a far more abundant cell type, in orchestrating behavior. Astrocytes form an integral part of the synaptic machinery and a single astrocyte can contact and influence the function of about 1,00,000 synapses. They are highly important for normal synaptic function and many brain disorders are associated with astrocytic dysfunction. We are interested in studying how astrocytes and neurons communicate with each other to modulate synaptic plasticity. We investigate the role of astrocytes in behavior with a particular emphasis on mood-related disorders such as anxiety and depression. We are currently studying Jagged-Notch signaling at astrocyte-neuron interfaces.
Role of astrocytes in behavior and disease