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Sanjay Gupta Aimée M. Dudley David Buchanan Drena Dobbs Karin S Dorman Dr. Xun Gu Thomas Peterson IRFAN AHMAD ANSARI John Golin Jannice Friedman Vimla Aggarwal Andrea Rinaldi Carmen Argmann Eleanor Maine Albertini Alessandra Judith Greenberg Mark Clark John F. Hayes Ashok Kumar Roger I. Cue View More
STEFANO CACCHIONE

Researcher
Department of Biology and biotechnology
University La Sapienza
Italy

Professor Genetics
Biography

1985 Laurea in Biological Sciences (110/110 cum laude), Sapienza University, Rome 1987-1989 ENI fellowship, Dept. of Genetics & Molecular Biology, Sapienza University. 1995, 1999 Post-doc, Dept. of Biochemistry & Molecular Biology, University of Valencia, Spain 2001-2010 Researcher, Dept. of Genetics & Molecular Biology, Sapienza University. Since 2010 Researcher, Dept. of Biology & Biotechnology, Sapienza University.

Research Intrest

Structure and function of human telomeric chromatin Interplay between telomeric nucleosomes and the human telomeric proteins TRF Epigenetic status of human telomeres Telomere organization in normal and cancer cells Structural organization of drosophila telomeres

List of Publications
Franceschin M, Nocioni D, Biroccio A, Micheli E, Cacchione S, Cingolani C, Venditti A, Zizza P, Bianco A, Altieri A. Design and synthesis of a new dimeric xanthone derivative: enhancement of G-quadruplex selectivity and telomere damage. Organic & biomolecular chemistry. 2014;12(47):9572-82.
Galati A, Micheli E, Alicata C, Ingegnere T, Cicconi A, Pusch MC, Giraud-Panis MJ, Gilson E, Cacchione S. TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization. Nucleic acids research. 2015 May 20;43(12):5824-37.
Burla R, Carcuro M, Raffa GD, Galati A, Raimondo D, Rizzo A, La Torre M, Micheli E, Ciapponi L, Cenci G, Cundari E. AKTIP/Ft1, a new shelterin-interacting factor required for telomere maintenance. PLoS genetics. 2015 Jun 25;11(6):e1005167.
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