Associate Professor
Comparative Biomedical Sciences
Louisiana State University
United States of America
DVM - College of Veterinary and Animal Sciences, Palampur, India, 2003 MS - Indian Veterinary Research Institute, Izatnagar, India, 2005 PhD - Michigan State University, East Lansing, MI, 2010 Postdoctoral fellowship - National Institute of Environmental Health Sciences, Research Triangle Park, NC, 2015 Residency in Anatomic Pathology - Louisiana State University, Baton Rouge, LA, 2016
Innate immunity is a highly conserved response that quickly detects and attempts to clear pathogens and harmful environmental stimuli by inducing inflammatory responses. These responses are orchestrated via temporal and highly coordinated regulation of a number of genes. In addition to regulation at the transcriptional level, a majority of these genes are also regulated by post-transcriptional mechanisms that modify mRNA stability and/or translation. The focus of our research is to understand the association between environmental stimuli, post-transcriptional mechanisms of gene expression, and disease pathogenesis. We are specifically interested in: 1) understanding how environmental exposures affect post-transcriptional mechanisms, in order to cause inflammation and immune-mediated disease; 2) understanding how post-transcriptional mechanisms induce changes in gene expression that confer competitive advantage to cancerous cells and contribute to tumor development.