Shwetal Mehta

Assistant Professor
Neurobiology
Barrow Neurological Institute
United States of America

Biography

Dr. Shwetal Mehta received her MS from Tata Institute of Fundamental Research, India, in Molecular Biology. She earned her PhD in Molecular Genetics and Microbiology from The University of Texas at Austin in 2003. She completed her postdoctoral work in the Charles Stiles Laboratory at the Dana-Farber Cancer Institute and Harvard Medical School. Her postdoctoral work was focused on the identification of a potential therapeutic target for high-grade gliomas. She joined the Barrow Brain Tumor Center as an principal investigator in January of 2013.

Research Intrest

Malignant gliomas, oligodendrocyte transcription factor

List of Publications

1. Singh SK, Fiorelli R, Kupp R, Rajan S, Szeto E, Cascio CL, Maire CL, Sun Y, Alberta JA, Eschbacher JM, Ligon KL. Post-translational modifications of OLIG2 regulate glioma invasion through the TGF-Î² pathway. Cell reports. 2016 Jul 26;16(4):950-66.
2. Kupp R, Shtayer L, Tien AC, Szeto E, Sanai N, Rowitch DH, Mehta S. Lineage-restricted OLIG2-RTK signaling governs the molecular subtype of glioma stem-like cells. Cell reports. 2016 Sep 13;16(11):2838-45.
3. Meijer DH, Sun Y, Liu T, Kane MF, Alberta JA, Adelmant G, Kupp R, Marto JA, Rowitch DH, Nakatani Y, Stiles CD. An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells. Journal of Neuroscience. 2014 Jun 18;34(25):8507-18.

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