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Shobhona Sharma

Professor
Department of Biological Sciences
Tata Institute of Fundamental Research
Iceland

Professor Biomedical Sciences
Biography

 Dr. Shobhona Sharma is a Senior Professor in the Department of Biological Sciences. Her lab is  exploring various aspects of biology of the malaria parasite (Plasmodium species) and the host-parasite interactions, during the red blood cell (RBC) stages of the infection. We study acquired immunity to malaria, as well as metabolic changes caused by the infection in the host, through the course of the disease. We also assess flexibility and dynamics of parasite infected RBCs using optical tweezers. In collaboration with ICT, Mumbai, we explore nanolipid carrier-mediated delivery of antimalarials. We have also initiated a study on the effect of mild malaria in the brain of the vertebrate host.

Research Intrest

 Biology of malarial parasite.

List of Publications
Das S, Rajagopal S, Sivakami S, Sharma S (2012) Erythrocytic stage dependent regulation of oligomerization of Plasmodium ribosomal protein P2. Journal of Biological Chemistry 287:41499.
Das S, Basu H, Sivakami S, Tewari R, Sharma S (2012) Arrest of nuclear division in Plasmodium through blockage of erythrocyte surface exposed ribosomal protein P2. PLOS Pathogens 8:e1002858.
Jain SA, Basu H, Prabhu PS, Soni U, Joshi MD, Mathur D, Patravale VB, Pathak S, Sharma S (2014) Parasite impairment by targeting Plasmodium-infected RBCs using glyceryl-dilaurate nanostructured lipid carriers. Biomaterials 35:6636.
Experts in Iceland
Anna Sigríður Ólafsdóttir János Szabó Zoltan Bajko Sanjit Kumar Chakraborty DR. SHEIKH ZAHOOR AHMAD Dr. Hafrun Fridriksdottir Asgeirsson, Thor Davidson, Mary Georgsson, Ludvik Hermann Kristjánsson Buck Sutter Haraldsson, Ingimar Dr. Harikrishna Varma P. R. Hjálmarsdóttir, Erla KÁRI STEFÁNSSON TANYA ZHAROV UNNUR ÞORSTEINSDÓTTIR C. AUGUSTINE KONG, Ph.D. PATRICK SULEM HILMA HÓLM GÍSLI MÁSSON ÞÓRUNN RAFNAR HREINN STEFÁNSSON INGILEIF JÓNSDÓTTIR JOHANN HJARTARSON View More