Seale Andre P.

Assistant Professor
Department Of Human Nutrition, Food and Animal Sciences
University of Hawaii
United States of America

Professor Nutrition
Biography

Currently Working on: Acclimation of fish to extreme environments and the effects of environmental stressors on fish physiology. Specifically, 1) Pituitary control of osmoreception and osmoregulation in a euryhaline fish model; 2) the effects of environmental salinity regime on fish growth; and 3) the effects of environmental contaminants on fish growth and reproduction.

Research Intrest

Extension/Research Interests: With broader implications to aquaculture and biomedical research, my main interests are in: 1) osmoreception: the signal transduction of environmental salinity changes into physiological responses at the cellular and organismic levels in fish; regulation of prolactin cells by external and neuroendocrine factors and the role of second messenger systems; 2) osmoregulation: salt and water balance and its interplay with growth, metabolism and stress in fish; and 3) environmental adaptation and growth in fish: endocrine and specialized cellular responses to changing environmental conditions.

List of Publications
Inokuchi, M., Breves, J., Moriyama, S., Watanabe, S., Kaneko, T., Lerner, D. T., Grau, E. G., Seale, A. P. (2015). Prolactin 177, prolactin 188 and extracellular osmolality independently regulate the expression of ion transport effectors in the gills of Mozambique tilapia. Am. J. Physiol. 309(10): R1251-1263.
Yamaguchi, Y., Takagi, W., Kuraku, S., Moriyama, S., Bell, J. D., Seale, A. P., Lerner, D. T., Grau, E. G., Hyodo, S. (2015). Discovery of conventional prolactin from the holocephalan elephant fish, Callorhinchus milii. Gen. Comp. Endocrinol. 224, 216-227.
Breves, J., Inokuchi, M., Yamaguchi, Y., Seale, A. P., Watanabe, Lerner, D. T., S., Kaneko, T., Grau, E. G. (2016). Hormonal regulation of aquaporin 3 in tilapia gill: opposing actions of prolactin and cortisol. J. Endocrinol. 230, 325-337.