Salim Merali

Professor
Moulder Center for Drug Discovery Research
Temple University
United States of America

Biography

Dr. Merali received his BS, MS, and PhD degrees in Biochemistry from The City University of New York. While completing his doctoral program, Dr. Merali joined New York University (1992-2005) to work on drug development on opportunistic fungal pathogens in AIDS (Pneumocystis). He also developed state of the art technology in Proteomics and Metabolomics. He joined Temple University School of Medicine (2005-2013) as Associate Professor of Biochemistry, The Fels Institute of Cancer Research and Molecular Biology, and Director of the Proteomics Core Facility. He became a member of Fox Chase Cancer Institute in 2012. Dr Merali joined the School of Pharmacy in 2013. Dr. Merali is an expert in the study of Pneumocystis infection and the use of S-adenosylmethionine as a marker for monitoring infection. He has been a key liaison for translational medicine research with regards to teaching and supervising infectious disease fellow, surgical residents and graduate students. He has vast expertise in Proteomics and Metabolomics applied to biomarker discovery, disease pathogenesis and identification of novel drug targets in COPD, obesity/diabetes, cancer, Pneumocystis, and neuroAIDS. He is the principal author of 7 patents. He is also the principal author or co-author of 68 publications. He is a member of several NIH study sections and has been invited to many lectureships.

Research Intrest

Dr. Merali research interestsinclude Proteomics and Metabolomics applied to biomarker discovery, disease pathogenesis and identification of novel drug targets in COPD, obesity/diabetes, cancer, Pneumocystis, and neuroAIDS. 

List of Publications
Merali S, Barrero CA, Bowler RP, Chen DE, Criner G, et al. (2014) Analysis of the plasma proteome in COPD: Novel low abundance proteins reflect the severity of lung remodeling. COPD: Journal of Chronic Obstructive Pulmonary Disease 11:177-189.
Boden G, Cheung P, Salehi S, Homko C, Loveland-Jones C, et al. (2014) Insulin regulates the unfolded protein response in human adipose tissue. Diabetes 63:912-922.
Morada M, Pendyala L, Wu G, Merali S, Yarlett N (2013) Cryptosporidium parvum induces an endoplasmic stress response in the intestinal adenocarcinoma HCT-8 cell line. Journal of Biological Chemistry 288:30356-30364.

Global Scientific Words in Pharmaceutical Sciences