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Ronald J. Midura

Staff
Biomedical Engineering
Cleveland Clinic Lerner Research Institute
United States of America

Professor Medicine
Biography

"Bone is a dynamic organ system exhibiting continual remodeling. These processes are dependent on the metabolic activity of bone cells: osteoblasts form bone, osteocytes maintain bone, and osteoclasts resorb bone. Nearly all bone diseases, or pathologies in fracture healing, manifest aberrations in bone matrix production and/or mineralization."

Research Intrest

Ronald has experience and sound knowledge in Skeletal biology; bone formation; metabolic bone disease; fracture healing; microgravity; space medicine; mechanical unloading

List of Publications
Wen D, Androjna C, Vasanji A, Belovich J, Midura RJ(2010 Lipids and collagen matrix restrict the hydraulic permeability within the porous compartment of adult cortical bone. Ann Biomed Eng. Mar;38(3):558-69.
Gorski JP, Huffman NT, Chittur S, Midura RJ, Black C, et al. (2011) Inhibition of proprotein convertase SKI-1 blocks transcription of key extracellular matrix genes regulating osteoblastic mineralization. J Biol Chem.
Androjna C, McCabe NP, Cavanagh PR, Midura RJ, (2011) Effects of Spaceflight and Skeletal Unloading on Bone Fracture Healing. Clinic Rev Bone Miner Metab.
Experts in United States of America
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