Rob Field

Professor
Biological Chemistry
John Innes Center
United Kingdom

Professor Biochemistry
Biography

Professor Rob Field and his research group joined John Innes Centre in Norwich in 2007. The group contributed by bringing an expertise in Chemistry and Biochemistry of carbohydrates which was useful to various projects carried out in collaboration with many scientist at JIC and Norwich Research Park. All our current research theme are in interface between chemistry and biology with projects aiming at better understanding of biological processes involving carbohydrates. Biosyntheis of starch and its degradation, glycoenzyme assays and manipulation with NDP sugar substrates, assembly of plant cell wall polysaccharides and manipulation with glycans from bacteria, we study all these and more in the wonderful enviroment of the John Innes Centre.

Research Intrest

Research in the Field group is focused on developing and exploiting chemical tools and principles to address questions in plant and microbial carbohydrate metabolism. Projects typically involve some combination of chemical and enzymatic synthesis, inhibitor design and assessment, biochemistry, structural biology, metabolomic, proteomic and transcriptomic analysis. From a biology perspective, we work cross-Kingdom: Arabidopsis, barley, Euglena, Streptomyces, E. coli, flu virus, the African and American trypanosome.

List of Publications
Ndeh D, Rogowski A, Cartmell A,Luis AS, Baslé A, et al. (2017) Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature 544: 65–70.
Wagstaff BA, Vladu IC, Barclay JE, Schroeder DC, Malin G, et al. (2017) Isolation and Characterization of a Double Stranded DNA Megavirus Infecting the Toxin-Producing Haptophyte Prymnesium parvum. Viruses 9pii: E40.
Møller SR, Yi X, Velásquez SM, Gille S, Hansen PL, Poulsen CP, et al. (2017) Identification and evolution of a plant cell wall specific glycoprotein glycosyl transferase, ExAD. Sci Rep 7: 45341.

Global Scientific Words in Biochemistry