Dr. Guo received an M.D. from Normal Bethune University of Medical Sciences in Changchun, P.R. China in 1992 and an M.S. in Immunology from the Institute of Radiation Medicine in Beijing, P.R. China. He served as Assistant Professor from 1997-199 at Beijing Institute of Infectious Diseases. In 1998, he joined the Joint Genomic Pathology Laboratory (University of Michigan, Department of Pathology and Pfizer Global Research and Development) as a Post-Doctoral Fellow. He is a member of the International Cytokine Society, the American Society of Human Genetics and the American Association of Immunologists. In 2001, he was appointed Research Investigator and was promoted to the rank of Research Assistant Professor in 2003. In 2007, Dr. Guo became an Adjunct faculty member and in September 2009, was promoted to the rank of Adjunct Research Associate Professor.

 Dr. Guo's research interests include the areas of cytokines/chemokines, apoptosis and sepsis. Dr. Guo has specialized expertise in the area of using mass-spectroscopy as a way to define small molecules produced during inflammatory reactions in rodents and will apply new iRNA strategy to define inflammatory meachansims of lung injury. He identified the novel cytokine, eotaxin-3 which has proven to be an important mediator in allergic inflammation and his studies have also demonstrated that complement C5a plays an important role in thymocyte apoptosis in sepsis.