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Philippa Hulley

Professor
Rheumatology
Kennedy Institute of Rheumatology Trust (Charing Cross Sunley Research Centre)
United Kingdom

Professor Orthopaedics
Biography

Associate Professor Hulley studied pattern formation during a developmental biology PhD at the University of Cape Town, South Africa, and followed this with post-doctoral work on cell signal transduction pathways in the Basel Preclinical Research Laboratories of Sandoz Pharma AG She joined the University of Stellenbosch, South Africa, as a Senior Scientist/Lecturer in 1996, and focused on mapping the changes in normal osteoblast signalling that are produced by clinical doses of glucocorticoids and which cause steroid osteoporosis.  Moving to Oxford, Assoc. Prof. Hulley was awarded a 5 year Arthritis Research UK Fellowship in 2004, University Research Lectureship in 2005, followed in 2007 by a 5 year RCUK Fellowship, teaching as Academic Fellow at St Hilda's College.  Since 2012, she has been University Lecturer in Musculoskeletal Sciences and a Tutorial Fellow at St Hilda's College. Research Interests: Rheumatology 

Research Intrest

Rheumatology

List of Publications
"1. Poulsen RC, Knowles HJ, Carr AJ, Hulley PA Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure Cell Death Dis (2014) Vol 5 2. Kuzma-Kuzniarska M, Yapp C, Pearson-Jones TW, Jones AK, Hulley PA Functional assessment of gap junctions in monolayer and three-dimensional cultures of human tendon cells using fluorescence recovery after photobleaching J Biomed Opt (2014) Vol 19 3. Poulsen RC, Watts AC, Murphy RJ, Snelling SJ, Carr AJ, Hulley PA. Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence. Ann Rheum Dis (2014) 73: 1405-1413. 4. Poulsen RC, Carr AJ, Hulley PA. Protection against glucocorticoid-induced damage in human tenocytes by modulation of ERK, Akt, and forkhead signaling. Endocrinology (2011) 152: 503-514. 5. Liang M, Russell G, Hulley PA. Bim, Bak, and Bax regulate osteoblast survival. J Bone Miner Res (2008) 23: 610-620.
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