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Krishna Sundari Kenneth C. Carroll Roy D. Welch Ratan Gachhui Lacy Daniels Hardik Pathak Varsha Gupta Smriti Gaur Alok Kalra Franklin, Portugal Mohammad Hayatul Islam Professor Clive Ronson Anthony Garza Joseph Ashour Evelyn de Souza Oliveira Lopes Alexander Borisovich Prikhodko Prof. M.S. Dkhar Prof. H. Kayang Rizwana Rahim Dr. Papiya Ramanujam View More
Peter Fineran

Professor
Microbiology & Immunology
Otago University
New Zealand

Professor Microbiology
Biography

Accumulating evidence demonstrates that viruses are the most abundant biological entities on the planet. They outnumber bacteria by approximately 10 to 1 and there are an estimated >1030 tailed bacteriophages globally! The result is an obvious selective pressure for bacteria to acquire resistance to phage attack and for phage to acquire counter defence mechanisms. Indeed, many mechanisms of phage resistance are known, ranging from bacterial cell surface alterations, through restriction and modification, to abortive infection

Research Intrest

Our research goal is to understand the interactions between mobile genetic elements, such as bacteriophages and plasmids, and their bacterial hosts. Our main interest is in phage resistance mechanisms.

List of Publications
Wilkinson, M.E., Nakatani, Y., Staals, R.H.J., Kieper, S.N., Opel-Reading, H.K., McKenzie, R.E., Fineran, P.C.# and Krause, K.L.# (2016). Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system. Biochemical Journal. 473. 1063-1072
Panda, P., Vanga, B.R., Lu, A., Fiers, M., Fineran, P.C., Butler, R., Armstrong, K., Ronson, C.W. and Pitman, A.R. (2016). Pectobacterium atrosepticum and Pectobacterium carotovorum harbor distinct, independently acquired integrative and conjugative elements encoding coronafacic acid that enhance virulence on potato stems. Frontiers in Microbiology. 7. 397
Hampton, H.G., McNeil, M.B., Paterson, T.J., Ney, B., Williamson, N.R., Easingwood, R.A., Bostina, M., Salmond, G.P.C. and Fineran, P.C.# (2016). CRISPR-Cas gene editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia. Microbiology. 162. 1047-1058
Experts in New Zealand
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