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Nukhet Aykin-Burns

Assistant Professor
Pharmaceutical Sciences Member, Division of Radiation Health
University of Arkansas
United States of America

Professor Pharmaceutical Sciences
Biography

Nukhet Aykin-Burns, Assistant Professor of Pharmaceutical Sciences Member, Division of Radiation Health, E-mail address: [email protected] Dr. Aykin-Burns received her Ph.D. degree from the University of Missouri-Rolla (currently known as Missouri University of Science and Technology) focusing on antioxidant-based therapies in lead poisoning. She received postdoctoral training at the Free Radical and Radiation Biology Program (FRRBP), Department of Radiation Oncology at the University of Iowa.

Research Intrest

Dr. Aykin-Burns’s research focuses on reactive oxygen species (ROS), radiation induced (IR and UV) normal tissue damage and wound healing as well as polychlorinated biphenyl (PCB) induced oxidative stress.

List of Publications
Aykin-Burns, N., Ahmad, I. M., Zhu, Y., Oberley, L. and Spitz, D. R. (2009) Increased levels of superoxide and hydrogen peroxide mediate the differential susceptibility of cancer cells vs. normal cells to glucose deprivation. Biochem J 418, 29-37. PMID:18937644
Zhu, Y., Kalen, A.L., Li, L., Lehmler, H.J., Robertson, L.W., Goswami, P.C., Spitz, D.R., Aykin-Burns, N. (2009) Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure. Free Radic Biol Med 47, 1762-1771. PMID:19796678
Kim, H.S., Patel, K., Muldoon-Jacobs, K., Bisht, K.S., Aykin-Burns, N., Pennington, J.D., van der Meer, R., Nguyen, P., Savage, J., Owens, K.M., Vassilopoulos, A., Ozden, O., Park, S.H., Singh, K.K., Abdulkadir, S.A., Spitz, D.R., Deng, C.X., Gius, D. (2010) SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress. Cancer Cell 17, 41-52. PMID:20129246
Ross C., Alston, M., Bickenbach, J.R., Aykin-Burns, N. (2011) Oxygen tension changes the rate of migration of human skin keratinocytes in an age-related manner. Exp Dermatol 20:58-63. PMID:21158939
Aykin-Burns, N., Slane, B.G., Liu, A.T.Y., Owens, K.M., O’Malley, M.S., Smith, B.J., Domann, F.E., Spitz, D.R. (2011) Sensitivity to low dose/low LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondrial derived reactive oxygen species. Radiat Res 175, 150-158. PMID:21268708

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