Biography

Lead of Musculoskeletal Epidemiology Deputy Director of ARUK Sports, Exercise and Osteoarthritis Centre of Excellence Fellow at the Lady Margaret Hall, University of Oxford Nigel Arden trained at St Thomas's Hospital, London, where he also completed four years of research into the genetics of osteoporosis. During this time, he gained an MSc in Epidemiology and an MD. He moved to the South Coast in 1996 and in 1998 spent six months as Visiting Assistant Professor in Epidemiology at the University of San Francisco. In February 2000 he commenced as Consultant Rheumatologist at Southampton General Hospital, and Senior Lecturer in Rheumatology at the University of Southampton. In April 2008 Nigel moved to his present post as Professor in Rheumatic Diseases and Consultant Rheumatologist, NDORMS, University of Oxford. Research Interests: Epidemiology of Osteoarthritis and Osteoporosis Expanding research programmes are based around: The complex genetic and environmental influences on Osteoarthritis and more importantly their interaction The epidemiology of knee and hip Osteoarthritis The epidemiology and survival of total joint replacements in Osteoarthritis The role of sport and exercise in Osteoarthritis Predicting outcome of patients with Osteoarthritis Personalized medicine and prevention of chronic diseases

Research Intrest

Epidemiology of Osteoarthritis and Osteoporosis

List of Publications
"1. Doherty M, McCaskie A, Willkinson JM, Ralston SH, Valdes AM, Spector TD, Loughlin J, Nigel Arden Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study Lancet (2012) 380: 815-823 2. Kritchevsky SB, Florez JC, Todd JA, Dupuis J, Hyppönen E, Spector TD, Nigel Arden Common genetic determinants of vitamin D insufficiency: a genome-wide association study Lancet (2010) 376: 180-188 3. Styrkarsdottir U, Thorleifsson G, Helgadottir HT, Bomer N, Nigel Arden Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31 Nat Genet (2014) 46: 498-502 4. Arden N, Richette P, Cooper C, Bruyère O, Abadie E, Branco J, Brandi ML Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Biomarkers and Frailty Drugs Aging (2015) 32: 525-535 5. Jackson KA, Sanchez-Santos MT, MacKinnon AL, Turner A, Kuznik K, Ellis S, Box C, Hill J, Javaid MK, Cooper C, Arden NK, Newton JL. Bone density and body composition in newly licenced professional jockeys. Osteoporos Int (2017).