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Nadine Bakkar

Assistant Professor
Department of Neurobiology
Barrow Neurological Institute
United States of America

Professor Neurology
Biography

Nadine Bakkar, PhD, is a research assistant professor in the Department of Neurobiology at Barrow Neurological Institute. Dr. Bakkar received her doctorate from The Ohio State University in molecular biology in the laboratory of Dr. Denis Guttridge, focusing on NF-kappaB signaling pathways involved in muscle development and regeneration. She completed two postdoctoral fellowships, one at The Ohio State University Comprehensive Cancer Center and one at Barrow Neurological Institute as part of Dr. Robert Bowser’s laboratory.

Research Intrest

Amyotrophic Lateral Sclerosis (ALS), Blood-CSF barriers disruptions, ALS pathogenesis

List of Publications
1. Balkhi MY, Iwenofu OH, Bakkar N, Ladner KJ, Chandler DS, Houghton PJ, London CA, Kraybill W, Perrotti D, Croce CM, Keller C. miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR. Science signaling. 2013 Jul 30;6(286).
2. Bakkar N, Boehringer A, Bowser R. Use of biomarkers in ALS drug development and clinical trials. Brain research. 2015 May 14;1607:94-107.
3. Bakkar N, Kousari A, Kovalik T, Li Y, Bowser R. RBM45 modulates the antioxidant response in amyotrophic lateral sclerosis through interactions with KEAP1. Molecular and cellular biology. 2015 Jul 15;35(14):2385-99.
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