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Experts in Nutrition
Linda J. Wykes Luis B. Agellon Kristine G. Koski Stan Kubow Grace S. Marquis Hugo Melgar-Quiñonez Hope A. Weiler Harriet V. Kuhnlein Katherine Gray-Donald Louise Thibault Mirey Karavetian Zainab Taha Axen, Kathleen Sergio A. Burgos Vilceu Bordignon Dr. Laura Palanker Musselman Carol A DeNysschen Amanda Newell Teresa Drake Jeannette Davidson View MoreNada A. Abumrad
Professor
Nutritional Science
Washington University School of Medicine
United States of America
Dr Abumrad’s group researches the molecular mechanisms regulating utilization of fatty acids and how abnormalities in fatty acid metabolism can result in metabolic disease such as obesity and diabetes. She identified the plasma membrane protein CD36 as a facilitator of cellular fatty acid uptake and is now examining the role of CD36 in modulating tissue adaptation to nutrient fluctuations and other stresses. Mice models of tissue-specific variations in CD36 gene level are being studied but the goal is to translate findings in rodents to humans where polymorphisms in the CD36 gene are common. A current project in humans is exploring (in collaboration with Alan Permutt and Sam Klein) whether mutations in CD36 are associated with an increased risk of insulin resistance and diabetes.
fatty acids, obesity, diabetes, molecular mechanisms,cellular fatty acid