Muhammad Ansar

Associate Professor
Biochemistry
Quaid-i-Azam University
Pakistan

Professor Genetics

Biography

Muhammad Ansar obtained his Ph.D. from Quaid-i-Azam University, Islamabad. He currently holds as an Associate Professor in Department of Biochemistry at Quaid-i-Azam University Islamabad. His Research interest mainly involved in the identification and characterization of genes responsible for retinal and neurological disorders. We are currently using commercially available SNP microarray platforms for the genetic analysis of large families with retinal and neurological disorders. Our pilot work on these disorders revealed the role of methylation and glycosylation in the human neuro developmental disorders. However exploration of additional players involved in multi component complexes involved in methylation and glycosylation will enable us to understand neurodevelopment processes in a better way. These players will be identified through genetic analysis of additional families and integration of data from expression studies and protein interaction maps. Additionally our group is also working on large scale genomic analysis, expression studies related to cancers and copy number analysis.

Research Intrest

Genetic

List of Publications

Ali G, Lee K, Andrade PB, Basit S, Santos-Cortez RL, Chen L, Jelani M, Ansar M, Ahmad W, Leal SM. Novel autosomal recessive nonsyndromic hearing impairment locus DFNB90 maps to 7p22.1-p15.3. Hum Hered. 2011;71(2):106-12.

Â Â Rafiq MA, Kuss AW, Puettmann L, Noor A, Ramiah A, Ali G, Hu H, Kerio NA, Xiang Y, Garshasbi M, Khan MA, Ishak GE, Weksberg R, Ullmann R, Tzschach A, Kahrizi K, Mahmood K, Naeem F, Ayub M, Moremen KW, Vincent JB, Ropers HH, Ansar M, Najmabadi H. Mutations in the Alpha 1,2-Mannosidase Gene, MAN1B1, Cause Autosomal-Recessive Intellectual Disability. Am J Hum Genet. 2011 Jul 15;89(1):176-82.

Khan S, Habib R, Mir H, Umm-E-Kalsoom, Naz G, Ayub M, Shafique S, Yamin T, Ali N, Basit S, Wasif N, Kamran-Ul-Hassan Naqvi S, Ali G, Wali A, Ansar M, Ahmad W. Mutations in the LPAR6 and LIPH genes underlie autosomal recessive hypotrichosis/woolly hair in 17 consanguineous families from Pakistan.Â Clin Exp Dermatol. 2011 Aug;36(6):652-4.

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Experts in Genetics

Muhammad Ansar

Ali G, Lee K, Andrade PB, Basit S, Santos-Cortez RL, Chen L, Jelani M, Ansar M, Ahmad W, Leal SM. Novel autosomal recessive nonsyndromic hearing impairment locus DFNB90 maps to 7p22.1-p15.3. Hum Hered. 2011;71(2):106-12.

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