Biography

Prof. Dustin has a B.A. in Biology from Boston University (1984) and a Ph.D. in Cell and Developmental Biology from Harvard University (1990). Research Interest- Immunology MAJOR FUNDING - Wellcome Trust Principal Research Fellowship - Translation of the Immunological Synapse He collaborated on new intravital microscopy projects with Wenbiao Gan, Dan Littman, Juan Lafaille, Michel Nussensweig, Dorian McGavern and Sandra Demaria among others. Continuation of work on the immunological synapse led to a basic description of the supramolecular assemblies that make up the mature immunological synapse

Research Intrest

Immunology, Biology, Cell and Developmental Biology

List of Publications
1. Mayya V, Neiswanger W, Medina R, Wiggins CH, Dustin ML Integrative analysis of T cell motility from multi-channel microscopy data using TIAM J Immunol Methods (2015) 416: 84-93 2. Kumari S, Depoil D, Martinelli R, Judokusumo E, Carmona G, Gertler FB, Kam LC, Carman CV, Burkhardt JK, Irvine DJ, Dustin ML Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway (2015) Elife Vol 4 3. Grakoui A, Bromley SK, Sumen C, Davis MM, Shaw AS, Allen PM, Dustin ML Pillars article: The immunological synapse: a molecular machine controlling T cell activation Science (1999) 285: 221-227 4. Choudhuri K, Llodrá J, Roth EW, Tsai J, Gordo S, Wucherpfennig KW, Kam LC, Stokes DL, Dustin ML Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse Nature (2015) 507: 118-123 5. Biswas KH, Hartman KL, Yu CH, Harrison OJ, Song H, Smith AW, Huang WY, Lin WC, Guo Z, Padmanabhan A, Troyanovsky SM, Dustin ML, Shapiro L, Honig B, Zaidel-Bar R, Groves JT. E-cadherin junction formation involves an active kinetic nucleation process. Proc Natl Acad Sci (2015) 12: 10932-10937.