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Jairaj K. Acharya Thomas P. Fondy Swarnali Acharyya Bachir Alobeid Richard Baer Aneel K Aggarwal Margaret H Baron Benjamin O. Anderson Parveen Bhatti Marita Zoma Chu Chen Eric Chow Giuseppina Carbone Asma Amleh Katia Basso Govind Bhagat Shiuan Chen Casey L. Daniel WenYong Chen Natalie R. Gassman View More
Mei Kong

Associate Professor
Cancer Biology
Beckman Research Institute
United States of America

Professor Oncology
Biography

Dr. Kong's research lab aims to delineate the strategies used by tumor cells to survive periods of metabolic stress and then to develop novel therapies targeting nutrient sensing pathways of neoplastic cells. Currently their research focuses on protein phosphatase 2A (PP2A) complexes in regulation of cancer cell survival upon nutrients deprivation.

Research Intrest

Cancer Biology Cell Signaling Cancer Metabolism

List of Publications
Tumor-associated mutant p53 promotes cancer cell survival upon glutamine deprivation through p21 induction
Reid MA, Lowman XH, Pan M, Tran TQ, Warmoes MO, Gabra MB, Yang Y, Locasale JW, Kong M. IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3. Genes & development. 2016 Aug 15;30(16):1837-51.
Pan M, Reid MA, Lowman XH, Kulkarni RP, Tran TQ, Liu X, Yang Y, Hernandez-Davies JE, Rosales KK, Li H, Hugo W. Regional Glutamine Deficiency in Tumours Promotes De-differentiation through Inhibition of Histone Demethylation. Nature cell biology. 2016 Oct;18(10):1090.
Experts in United States of America
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