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Experts in Genetics
Sanjay Gupta Aimée M. Dudley David Buchanan Drena Dobbs Karin S Dorman Dr. Xun Gu Thomas Peterson IRFAN AHMAD ANSARI John Golin Jannice Friedman Vimla Aggarwal Andrea Rinaldi Carmen Argmann Eleanor Maine Albertini Alessandra Judith Greenberg Mark Clark John F. Hayes Ashok Kumar Roger I. Cue View MoreMAZZONI CRISTINA
Associate professor
Department of Biology and biotechnology
University La Sapienza
Italy
She is working as an associate professor at University of Rome (Sapienza), Rome, Italy. She exploited the power of yeast molecular genetics to delucidate the molecular basis of both aging and apoptosis. In particular, they study the role of mRNA degradation in regulating apoptosis and aging in yeast. They found that the stabilization of mRNAs, following mutations in genes involved in the decapping process ( dcp1, dcp2 and lsm1-7 ) triggers apoptosis and accelerates chronological aging. Using one of these mutants (lsm4Δ1) they have been isolated from a genomic bank by some multicopy suppressors of apoptotic phenotypes and we are currently studying the molecular mechanisms of such suppression.
aging and genetics