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Matt Cruzen

Associate Professor
Biological Science
Biola University
United States of America

Professor Bioinformatics and Systems Biology
Biography

Matt Cruzen teaches various courses in the Biology Department including: Cell and Molecular Biology, Biochemistry and Microbiology. Cruzen’s research interests are focused on the process of aging in the nematode worm Caenorhabditis elegans. He and his students are looking at morphological development of different long lived and wild type worms. They analyze the surface characteristics of the pharynx and the vulva in developing and aging worms by scanning electron microscopy to identify chronological and developmental changes (worm wrinkles) in the two groups of worms. The basic question has to do with when wrinkles are acquired with respect to their physiological and chronological age.

Research Intrest

Cellular mechanisms of aging,Bacterial metabolism

List of Publications
Arfin, S.M., Gerken, S.C., Kontis, K.J., and Cruzen, M.E. "Threonyl-tRNA Synthetase Gene Amplification in Borrelidin Resistant Mammalian Cells", Gene Amplification in Mammalian Cells: Techniques and Applications. Kellems, R.E. (ed.), Marcel Dekker, Inc. New York, pp. 97-105, 1992.
Cruzen, M.E. Characterization of cDNAs and Genomic DNAs for Human Threonyl- and Cysteinyl-tRNA Synthetase. Doctoral Dissertation. University of California, Irvine, 1993.
Cruzen M.E. and Arfin, S.M. (1994). Nucleotide and Deduced Amino Acid Sequence of Human Cysteinyl-tRNA Synthetase. DNA Sequence-J. DNA Sequencing and Mapping vol 4, pp 243-248, 1994.

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