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Martha K. Cathcart

Emeritus Staff
Cellular and Molecular Medicine
Cleveland Clinic Lerner Research Institute
United States of America

Professor Medical Sciences
Biography

Martha's focus of our research is on defining the mechanisms responsible for LDL and lipid oxidation during the activation of human monocytes (HM) and to study the role of lipids in regulating HM activation and migration into sites of inflammation.

Research Intrest

Inflammation; atherosclerosis; glioblastoma; innate immunity; human monocyte/macrophages; lipoxygenase; chemotaxis; superoxide anion; signal transduction; gene expression

List of Publications
Hsi LC (2011) Silencing IL-13Ralpha2 promotes glioblastoma cell death via endogenous signaling. Mol Cancer Ther. 10(7):1149-1160.
Elsori DH (2011) Protein kinase C delta is a critical component of Dectin-1 signaling inprimary human monocytes. J Leukoc Biol. 2011, 90(3):599-611.
Bhattacharjee A ( 2011) Hck is a key regulator of gene expression in alternatively activated human monocytes. J Biol Chem. 2011, 286(42):36709-36723.

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