Larisa J Geskin

Professor
Dermatology
Columbia University Medical Center
United States of America

Professor Dermatology
Biography

Dr. Angela M. Christiano is currently employed at Skinetics Biosciences, Inc. He is a Co-Founder of the company

Research Intrest

The major focus of our research is the study of inherited skin and hair disorders in humans and mice, through a classical genetic approach including identification and phenotyping of disease families, genetic linkage, gene discovery and mutation analysis, and functional studies relating these findings to basic questions in epidermal biology. Our interests include transcriptional regulation of hair cycling and differentiation, the biology of cadherin-mediated cell adhesion junctions known as desmosomes, and the morphogenesis epidermal appendages such as hair and teeth. A long-range goal of our research is to develop genetic and cell-based therapies for skin and hair diseases through understanding disease pathogenesis. We are using epithelial reprogramming as a therapeutic approach for inherited skin diseases.

List of Publications
Bates SE and Geskin LJ (2016) Romidepsin Therapy Over 5 Years in a Clinical Setting-Real-world Experience. JAMA Oncol 2 : 794-5.
Dulmage BO, Akilov O, Vu JR, Falo LD and Geskin LJ (2015) Dysregulation of the TOX-RUNX3 pathway in cutaneous T-cell lymphoma. Oncotarget.
Geskin LJ (2015 ) Monoclonal Antibodies. 33 : 777-86.