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Komaraiah Palle

Assistant Professor
Oncologic Sciences
Mitchell Cancer Institute
United States of America

Professor Oncology
Biography

Dr.Komaraiah Palle is currently working as Assistant Professor at Department of Oncologic Sciences, Mitchell Cancer Institute (USA). He has received his Bachelors in Biology & Chemistry from Kakatiya University, India. Dr. Komaraiah Palle has received his Ph.D. in Genetics from Osmania University, India. Dr. Komaraiah Palle has many reviewed publications.

Research Intrest

Molecular carcinogenesis mechanisms, Genome instability syndromes (Fanconi anemia and BRCA genes),Ubiquitin ligases and their role in DNA damage response and repair, Cell cycle regulation and DNA replication, DNA topoisomerases and their inhibitors, Hedgehog/Gli1 signaling, Epigenetic mechanisms in regulation of cell cycle and DNA repair, Molecular cancer therapeutics, Mechanistic studies on natural and dietary compounds

List of Publications
Palle K, Vaziri C. Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition. Cell Cycle. 2011 May 15;10(10):1625-38.
Komaraiah P, Kishor PK, Carlsson M, Magnusson KE, Mandenius CF. Enhancement of anthraquinone accumulation in Morinda citrifolia suspension cultures. Plant science. 2005 May 31;168(5):1337-44.
Rani V, Deep G, Singh RK, Palle K, Yadav UC. Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies. Life sciences. 2016 Mar 1;148:183-93.
Koster DA, Palle K, Bot ES, Bjornsti MA, Dekker NH. Antitumour drugs impede DNA uncoiling by topoisomerase I. Nature. 2007 Jul 12;448(7150):213.
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