Justine Ellis

Professor
Cell Biology
Murdoch Childrens Research Institute
Australia

Professor Pediatrics
Biography

Dr Justine Ellis is an Australian Research Council Future Fellow and Group Leader of Genes, Environment and Complex Disease at Murdoch Childrens Research Institute. She trained as a complex disease geneticist at the University of Melbourne, with her early work focusing on adult diseases and traits. Upon moving to Murdoch Childrens in 2007, she established a multidisciplinary program of research called CLARITY - ChiLdhood Arthritis Risk factor Identification sTudY - along with Dr Jane Munro and other Murdoch Childrens and The Royal Children's Hospital colleagues. The design of CLARITY, which collects clinical, epidemiological and environmental data, along with multiple biospecimen types, recognises the multifactorial nature of diseases such as juvenile arthritis. It aims to individually consider the genetic, environmental and epigenetic factors in determining disease, but also importantly, the interplay between them. With the early support of internal and philanthropic funds, CLARITY has recruited over 1300 participants and has now attracted competitive grant funding from National Health and Medical Research Council and the Australian Research Council. Dr Ellis also collaborates widely with other research groups working on complex diseases including immune disorders, cardiovascular conditions, and mental health.

Research Intrest

Paediatrics,Genes, Environment & Complex Disease

List of Publications
Ellis JA, Chavez RA, Pezic A, Ponsonby AL, Akikusa JD, Allen RC, Munro JE. Independent replication analysis of genetic loci with previous evidence of association with juvenile idiopathic arthritis. Pediatric Rheumatology. 2013 Mar 18;11(1):12.
Ellis JA, Kemp AS, Ponsonby AL. Gene–environment interaction in autoimmune disease. Expert reviews in molecular medicine. 2014 Jan;16.
Valencia RA, Martino DJ, Saffery R, Ellis JA. In vitro exposure of human blood mononuclear cells to active vitamin D does not induce substantial change to DNA methylation on a genome-scale. The Journal of steroid biochemistry and molecular biology. 2014 May 31;141:144-9.