Julio A Aguirre-Ghiso

professor
Medicine, Hematology and Medical Oncology
Mount Sinai School of Medicine
United States of America

Professor Haematology
Biography

Director, Head and Neck Cancer Basic Research. Director of Solid Tumor and Metastasis Research. Division of Hematology and Oncology, Department of Medicine and Department of Otolaryngology Mount Sinai School of Medicine.

Research Intrest

Autophagy, Cancer, Cell Adhesion, Cell Motility, Extracellular Matrix, Gene Expressions, Gene Regulation, Integrins, Metastasis, Morphogenesis, Oncogenes, Signal Transduction, Stem Cells, Tumorigenesis

List of Publications
Wen HC, Avivar-Valderas A, Sosa MS, Girnius N, Farias EF, etal (2011) p38α Signaling Induces Anoikis and Lumen Formation During Mammary Morphogenesis. Science signaling 4 :174.
Gutiérrez-Uzquiza Á, Arechederra M, Bragado P, Aguirre-Ghiso JA, Porras A (2012) p38α mediates cell survival in response to oxidative stress via induction of antioxidant genes: effect on the p70S6K pathway. The Journal of biological chemistry PP: 287.
Sosa MS, Bragado P, Debnath J, Aguirre-Ghiso JA (2013) Regulation of tumor cell dormancy by tissue microenvironments and autophagy. Advances in experimental medicine and biology PP: 734.
Kim RS, Avivar-Valderas A, Estrada Y, Bragado P, Sosa MS, etal (2012) Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer. PloS one VOL: 7.
Bragado P, Estrada Y, Parikh F, Krause S, Capobianco C (2013) TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling. Nature cell biology PP: 15.