He is currently working as a Assistant Professor at National Chiayi University, Taiwan. He has completed his Ph.D., Texas A&M University. His Research Area： Biochemistry. One of his research plans is to study the etiology of spinal muscular atrophy (SMA) and to search for effective medication for the disease. SMA is an autosomal recessive genetic disease affecting motor neuron integrity. The motor neurons influence the voluntary muscles that are used for activities such as crawling, walking, and head and neck control etc. Individuals with SMA generally do not have a functional SMN1 (survival motor neuron 1) gene that produces SMN protein required for functional motor neurons. It is estimated that approximately 50 infants are the victims of SMA annually in Taiwan. However, there is no an effective drug to cure or postpone the onset of the disease. One of my research projects is to screen drugs or chemicals that are capable of altering the splicing pattern of SMN1 gene, the isoform of its products playing a critical role on the severity of spinal muscular atrophy (SMA). he had 24 publications.

etiology of spinal muscular atrophy