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Jairaj K. Acharya Thomas P. Fondy Swarnali Acharyya Bachir Alobeid Richard Baer Aneel K Aggarwal Margaret H Baron Benjamin O. Anderson Parveen Bhatti Marita Zoma Chu Chen Eric Chow Giuseppina Carbone Asma Amleh Katia Basso Govind Bhagat Shiuan Chen Casey L. Daniel WenYong Chen Natalie R. Gassman View More
Judith Singer-Sam

Professor
CANCER BIOLOGY
Beckman Research Institute
United States of America

Professor Oncology
Biography

Dr. Sam's group is studying possible mechanisms for such expression, Monoallelic expression is a characteristic of genes that are implicated in certain inherited disorders of the CNS as well as some cancers. Using clonal CNS-derived neural stem cells as a model system

Research Intrest

Epigenetics Mono-allelic Expression Central Nervous System

List of Publications
Wang J, Valo Z, Smith D, Singer-Sam J. Monoallelic expression of multiple genes in the CNS. PLoS One. 2007 Dec 12;2(12):e1293.
Wang J, Valo Z, Bowers CW, Smith DD, Liu Z, Singer-Sam J. Dual DNA methylation patterns in the CNS reveal developmentally poised chromatin and monoallelic expression of critical genes. PLoS One. 2010 Nov 4;5(11):e13843.
Li SM, Valo Z, Wang J, Gao H, Bowers CW, Singer-Sam J. Transcriptome-wide survey of mouse CNS-derived cells reveals monoallelic expression within novel gene families. PLoS One. 2012 Feb 22;7(2):e31751.
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