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Judith Agudo-Cantero

ASSISTANT PROFESSOR
Genetics and Genomic Sciences
Mount Sinai School of Medicine
United States of America

Professor Genetics
Biography

Dr. Judith Agudo did her graduate training at the University Autonomous of Barcelona. Her PhD worked focused on beta cell regeneration. She did her postdoctoral training in the Brown lab on the molecular regulation of the inflammatory response. During this time, she discovered a previously unrecognized pathway in which the miR-126/VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.

Research Intrest

Antigen Presentation, Dendritic Cells, T Cells

List of Publications
Agudo J, Ayuso E, Jimenez V, Casellas A, Mallol C, Salavert A, etal (2012) Vascular endothelial growth factor-mediated islet hypervascularization and inflammation contribute to progressive reduction of β-cell mass. Diabetes Vol: 61.
Agudo J, Ruzo A, Kitur K, Sachidanandam R, Blander JM, etal (2012) A TLR and non-TLR mediated innate response to lentiviruses restricts hepatocyte entry and can be ameliorated by pharmacological blockade. Molecular therapy : the journal of the American Society of Gene Therapy Vol: 20.
Helft J, Manicassamy B, Guermonprez P, Hashimoto D, Silvin A, etal (2012) Cross-presenting CD103+ dendritic cells are protected from influenza virus infection. The Journal of clinical investigation vol :122.
Anguela XM, Tafuro S, Roca C, Callejas D, Agudo J, Obach M, etal (2013) Nonviral-mediated hepatic expression of IGF-I increases Treg levels and suppresses autoimmune diabetes in mice. Diabetes Vol: 62.
Agudo J, Ruzo A, Tung N, Salmon H, Leboeuf M, etal (2014) The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids. Nature immunology Vol:15.
Israelow B, Mullokandov G, Agudo J, Sourisseau M, Bashir A, etal (2015) Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors. Nature communications Vol: 5.
Kidd BA, Wroblewska A, Boland MR, Agudo J, Merad M, Tatonetti NP, etal (2016) Mapping the effects of drugs on the immune system. Nature biotechnology vol: 34.
Agudo J, Ruzo A, Park ES, Sweeney R, Kana V, etal (2015) GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions. Nature biotechnology Vol: 33.
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