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Experts in Neurology
Eun-Young Lee Shahdat Hossain NITIN M. NAGARKAR Kevin A Roth Asa Abeliovich Dritan Agalliu Ottavio Arancio Edmund Au Francesca Bartolini Wu Anhua  Priti Balchandani Prof. Dr. Raghda Nasr Ibrahim Nasr Nassa Jacque Dalton Sara Johnston Dr. Ryoko Sasamoto Evans Spears Zachery Sneed Nadine Bakkar Dave Schroeder Jennifer Basil View MoreJuan Lerma
Principal Investigator
Cellular and Systems Neurobiology
The Instituto de Neurociencias de Alicante
Spain
Present and Previous positions • 2016-present: Editor-in-Chief of Neuroscience, • 2016-present: Secretary-General of the Federation of European Neuroscience Societies (FENS) • 2014-present: Member of the Board, European Brain Council • 2014-present: Member of the Executive Committee of the Confederation of Spanish Scientific Societies (COSCE) • 2007-2016: Director, Instituto Neurociencias de Alicante (CSIC-UMH) • 2013-16: Chairman of the PanEuropean Regional Committee of the International Brain Research organization (IBRO) (previously WERC+CEERC) • 2005-07. Vicedirector, Instituto Neurociencias de Alicante (CSIC-UMH) • 2000-03. Head of Department of Neural Plasticity. Instituto Cajal, CSIC • 2000. Profesor de Investigación CSIC • 1995: Acting Director. Instituto Cajal, CSIC • 1993-96: Vicedirector. Instituto Cajal, CSIC
Current line of research: All these data led us to conclude that KARs influence neuronal excitability and information transfer in the brain (see our 2013 Neuron review). However, the role played by KARs in brain physiology and even clearer in pathology is still much more poorly understood than that of other glutamate receptors. Our recent discovery that overexpressing one of the KAR high affinity subunits, GluK4, reproduces autism traits (J. Neurosci., 2015b) represents one of the most compelling demonstrations of their involvement in mental disease; but also that slightly altering the gain of particular synapses may significantly impact the behavior.