Jorge Manzanares Robles

Principal Investigator
Molecular Neurobiology
The Instituto de Neurociencias de Alicante
Spain

Professor Neurology
Biography

Degree: Pharmacist, specialist in Biochemistry by Universidad Complutense of Madrid in 1985. Ph.D program: PhD in Pharmacy “Cum Laude” by Universidad Complutense of Madrid in 1987. Thesis advisors: Prof. Francisco Zaragoza y Juana Benedí González. Posdoctoral Positions: Research Associate, Department of Pharmacology and Toxicology, Michigan State University from 2/1988 to 9/1993, in the laboratory of Dr. Kenneth E. Moore. Previous positions: 1980-81 Colaborator Department of Research, Hospital Ramón y Cajal, Madrid 1985-87 Predoctoral student, Department of Pharmacology, School of Pharmacy, UCM, Madrid 1985-87 Colaborator Department of Psychiatry, Hospital Ramón y Cajal, Madrid 1985-87 Colaborator Departmento of Clinical Biochemistry, Hospital La Paz, Madrid 1988-93 Research Associate-Department of Pharmacology, Michigan State Univ, USA 11/1993-1/94 Researcher contracted by Ministry of Education in Department of Pharmacology, School of Pharmacy, UCM, Madrid 2/94-8/94 Researcher contracted by National Research Council-Instituto Cajal, CSIC 9/94-12/94 Researcher contracted by Ministry of Education in Department of Pharmacology, School of Pharmacy, UCM, Madrid 1995-5/97 Researcher contracted by Ministry of Education -Instituto Pluridisciplinar and Department of Pharmacology, School of Pharmacy, UCM, Madrid 12/97-11/99 Researcher contracted by Ministry of Education in Instituto Pluridisciplinar and Department of Biochemistry and Molecualr Biology, UCM, Madrid 4/00-11/04 Researcher contracted by Ministry of Health Department of Psychiatry and Research Unit, Hospital 12 de Octubre, Madrid Current Position: Associated Professor in Pharmacology, Universidad Miguel Hernández since Novembre of 2004.

Research Intrest

Research Fields: Role of opioid and cannabinoid systems in the pharmacological therapies of psychiatric and neurological diseases.

List of Publications
Racz I. , Nadal X., Alferink J., Baños JE.,Rehnelt J.,Martin M., Pintado B.,Gutiérrez-Adán A.,Sanguino E.,Manzanares J., Bellora M.,Zimmer A.,Maldonado R. " Interferon-γ is a critical modulator of CB2 cannabinoid receptor signaling during neuropathic pain. " J Neurosci . 28(46) , 12136 - 12145 ( 2008 ) Racz I. , Nadal X., Alferink J., Baños JE., Rehnelt J., Martin M.,Pintado B.,Gutierrez-Adan A.,Sanguino E.,Manzanares J.,Zimmer A,Maldonado R. " Crucial role of CB2 cannabinoid receptor in the regulation of central immune responses during neuropathic pain. " J. Neurosci . 28(46) , 12125 - 12136 ( 2008 ) Rubio G. , Manzanares, J., Jiménez, M., Rodríguez-Jiménez, R., Martínez, I., Martín Iribarren, M., Jiménez-Arriero, M.A., Ponce, G., Palomo, T. " The use of cocaine in heavy drinkers increases the vulnerability for alcohol dependence: A four-year-follow-up study. " J. Clin. Psychiatry. . 69(4) , 563 - 570 ( 2008 ) Oliva JM , Manzanares J. " Gene transcription alterations associated to decrease of ethanol intake induced by naltrexone in brain regions of Wistar rats. " Neuropsychopharmacology . 32(6) , 1358 - 1369 ( 2007 )