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Jonathan Mark Brown

Assistant Staff
Cellular and Molecular Medicine
Cleveland Clinic Lerner Research Institute
United States of America

Professor Medicine
Biography

My research is focused on the interrelationship between lipid metabolism and the development of chronic diseases such as obesity, diabetes, and atherosclerosis. We have three active research programs, and we are always looking for highly motivated young scientists to participate in our multidisciplinary training program.

Research Intrest

Lipid metabolism; lipoprotein metabolism; atherosclerosis; obesity; diabetes; reverse cholesterol transport; triacylglycerol; nutrition.

List of Publications
Cantley JL, (2013) CGI-58 knockdown sequesters diacylglycerols in lipid droplets, preventing DAG-mediated PKCε translocation to the plasma membrane and hepatic insulin resistance. Proc. Natl. Acad. Sci USA 110(5): 1869-1874.
Lord CC, (2012) CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action. Diabetes 61(2): 355-363.
Temel (2010) Biliary sterol secretion is not required for macrophage reverse cholesterol transport. Cell Metab. 12(1): 96-102.
Experts in United States of America
Jairaj K. Acharya John Belote Wayde Brown Aimée M. Dudley Jon P Mochel Rabaa M. Al-Rousan Chancellor, Renate Karen Lee Abt Lin Li Hui-Hsien Chou Hamed I. Aly Cory K. Adams Mark Ehrensberger Jose Buitrago Gerhard J. Barone Jacquelyne Adams Jon Calabria Shelley Cannady Susan B. Adams Stoica George Daniel E. Acuna Tal Amasay Jason R. Wiles Matthew H Andersen Brian Rothman View More