John Subjeck

Professor
Department of Cell Stress Biology
Roswell Park Cancer Institute
United States of America

Professor Oncology
Biography

Dr. John R. Subjeck joined the staff of Roswell Park Cancer Institute (RPCI) in 1979, as a Cancer Research Scientist, Division of Radiation Biology, Department of Radiation Medicine. He was appointed Member in the Departments of Cell Stress Biology and Molecular and Cellular Biology in 1999, and is also a Professor of the Molecular & Cellular Biophysics and Biochemistry Roswell Park Graduate Division, University at Buffalo (UB).Dr. Subjeck earned his doctoral degree in Biophysical Sciences, UB School of Medicine & Biomedical Sciences in 1974. He completed a postdoctoral fellowship in Experimental Pathology at RPCI in 1977. From 1977-1979, Dr. Subjeck specialized in Hyperthermia as a Research Affiliate in Medical Physics in the Division of Radiation Biology at RPCI. He is certified by the American Board of Radiology in Therapeutic Radiological Physics.

Research Intrest

Heat shock/stress proteins and their use as anti-cancer vaccines.

List of Publications
Wang Y, Wang X-Y, Subjeck JR, Kim HL, (2010) Covalent crosslinking of tumor antigens stimulates an antitumor immune response Vaccine 28: 6613-6620
Wang XY, Sun X, Chen X, Facciponte J, Subjeck JR, et al. (2010) Superior antitumor response induced by large stress protein chaperoned protein antigen compared with peptide antigen. Journal of immunology 184: 6309-6319
Arnouk H, Zynda ER, Wang X-Y, Hylander BL, Subjeck JR, et al. (2010) Tumour secreted grp170 chaperones full-length protein substrates and induces an adaptive anti-tumour immune response in vivo. International journal of hyperthermia 26: 366-375