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Experts in Pathology
Dr. Sajjan Singh Surana Mahua Choudhury Joseph C. Gregorek Mireya correa Cory Abate-Shen Rosanna G. Abellar Abdul Samad Dr. Ahmed MagdyMetwallyAbd Al Hamid Ester Ballana Guix Jianguo (Jeff) Xia Jen Ronholm David Murdoch Peter D Canoll Susan Best Ryan Blaedow Sofia Avnet Lucio Montanaro Lynn K Carta Kurian P. Abraham Dr Gavin Hunter View MoreJohn D Altman, PhD
Faculty
Pathogens
International Vaccine Institute
United States of America
Our MHC tetramer technology has played an essential role in defining the distribution of T cell subsets specific for a variety of pathogens, and this continues to be a central focus of the work in our laboratory. We are interested in both defining the relationships between T cell phenotypes and effector functions that can be assessed using short-term in vitro assays (that do not require amplification of T cell populations), as well as using adoptive transfer experiments in mouse models that permit in vivo testing of the efficacy of purified T cell subsets.
specific for a variety of pathogens, and this continues to be a central focus of the work in our laboratory. We are interested in both defining the relationships between T cell phenotypes and effector functions that can be assessed using short-term in vitro assays