Dr. Wu pursued postdoctoral training at both the University of New Mexico and Tohoku University School of Medicine in Japan. He received his PhD from Sun Yet-Sen University of Medical Sciences and his MD from Xuzhou Medical College, both in China. Dr. Jie Wu joined Barrow in 1998 as a principal investigator and as Director of Epilepsy Research. Since 2000 he has overseen several research projects on the physiology, pharmacology, and pathophysiology of neuronal nicotinic acetylcholine receptors (nAChR) using both heterologously expressed and natural nAChRs. Dr. Wu also investigates the epileptogenesis of human gelastic seizures using surgically resected human hypothalamic hamartoma tissue from patients with gelastic seizures. He is a leader in the study of the epileptogenic mechanisms underlying human hypothalamic hamartomas. He has used his experience as an electrophysiologist to make significant contributions to the study of nAChRs. Since 2000, Dr. Wu’s laboratory has been published in more than 100 peer-reviewed papers. Dr. Wu has also contributed to six book chapters and owns four United States utility patents. He also serves on the editorial board for several scientific journals.

Nicotinic Acetylcholine Receptor (nAChR) Physiology, Pharmacology, and Pathophysiology, Cellular and Molecular Mechanisms of Epilepsy, Cellular Mechanisms of Neurodegeneration