Jean-François Bruxelle is specialized in host-pathogen interactions acquiring multidisciplinary knowledge in immunology, microbiology and pharmacology. During his PhD, he mastered skills and learned new techniques through vaccine development with characterization of antigens, their vectorization and immunizations assays followed by the study of the immune response induced. His current project focuses on the development of a mucosal vaccine strategy targeting colonization factors of Clostridium difficile. The objective is to induce a local protection against C. difficile colonization; which is the first stage of the infection. This strategy could prevent the inflammatory response as well as the dissemination of bacteria in the environment. Jean-François Bruxelle is specialized in host-pathogen interactions acquiring multidisciplinary knowledge in immunology, microbiology and pharmacology. During his PhD, he mastered skills and learned new techniques through vaccine development with characterization of antigens, their vectorization and immunizations assays followed by the study of the immune response induced. His current project focuses on the development of a mucosal vaccine strategy targeting colonization factors of Clostridium difficile. The objective is to induce a local protection against C. difficile colonization; which is the first stage of the infection. This strategy could prevent the inflammatory response as well as the dissemination of bacteria in the environment.

Vaccines & Vaccination