Jason Cannon

Associate Professor of Toxicology
School of Health Sciences
Purdue University
United States of America

Professor Toxicology
Biography

Jason Cannon is an Associate Professor of Toxicology in the School of Health Sciences at Purdue University in West Lafayette. He received his B.S. in Physiology from Michigan State University, his Ph.D. in Toxicology from the University of Michigan, and was a postdoctoral fellow at the Pittsburgh Institute of Neurodegenerative Diseases at the University of Pittsburgh. He teaches courses in analytical, pathological, and biochemical toxicology and performs mechanistic research on the environmental bases of Parkinson’s disease. His research group is particularly interested in the following topics related to Parkinson’s disease: 1) Neurotoxicity of heterocyclic amines, which are compounds formed during high temperature cooking; 2) How environmental insults may disrupt autophagy and lead to neuronal cell death; 3) How specific genetic factors can increase sensitivity to environmental insults. The lab utilizes neurobehavioral, biochemical, and histological techniques to address these topics.

Research Intrest

Dietary toxicants and neurological disease Environmentally-induced autophagy disruptions Gene-environment interactions in Parkinson’s disease

List of Publications
Griggs, A. M., Agim, Z. S., Mishra, V. R., Tambe, M. A., Director-Myska, A. E., Turteltaub, K. W., McCabe, G. P., Rochet, J. C. and Cannon, J. R. (2014). 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Is Selectively Toxic to Primary Dopaminergic Neurons In Vitro. Toxicol Sci 140: 179-89
Lee, J. W., Tapias, V., Di Maio, R., Greenamyre, J. T. and Cannon, J. R. (2015). Behavioral, neurochemical, and pathologic alterations in bacterial artificial chromosome transgenic G2019S leucine-rich repeated kinase 2 rats. Neurobiol Aging 36: 505-18