Professor Hou Shengtao is a world famous scholar neurobiology research scholar, in neurodegenerative diseases and nerve cell apoptosis and regeneration of the signal transduction molecular mechanism and gene therapy carried out in-depth study, and molecular neurobiology, Cell biology, neural disease molecular mechanism, gene therapy and genetic engineering and so has a profound professional basis. The Through extensive cooperation with the world's leading laboratories, a series of innovative achievements: (1) its pioneering work has proved that the axon-guided molecules of the new function, that is, during the stroke of the brain recovery process, axon-guided molecules involved in brain scars inhibition Sexual environment-mediated synaptic injury, axon shortening, and neuronal apoptosis signaling. Revealing the molecular mechanism of inhibition of brain function recovery, for the development of new drugs to promote the recovery of neurological function laid the foundation. (2) to prove that transcription factor E2F1 can mediate differentiation of mature nerve cell apoptosis, and E2F1 regulation of neuronal apoptosis and biochemical response mechanism and gene regulation pathways in-depth study. (3) Successful construction of hypoxia-induced, neuron-specific adenovirus expression vector is an important tool for studying ischemic-related neurodegenerative diseases such as stroke. It has important theoretical and potential clinical application value. These new scientific discoveries and technological innovations promote the recovery of functional brain injury by reducing the level of inhibitory factors after stroke. The long-term goal is to reduce the impact of stroke disability on national health systems and society New research direction, significant significance. 　　 Professor Hou Shengtao, Ph.D. In 1988 by the University of Glasgow (University of Glasgow) School of Medicine full scholarship, Ph.D., graduated in 1991. In the same year, the British Medical Research Council postdoctoral funding, has in the University of London Department of Neurology and the University of Bristol University Department of Biochemistry to do postdoctoral research. Since 1996, he was employed by the Institute of Life Sciences of the National Academy of Sciences in Canada and was awarded the position of senior researcher. He is the head of the Department of Biomedical, Cerebrovascular Disease, and Director of the Biosafety Committee of the Institute of Life Sciences, National Institute of Life Sciences, Canada. He is also a professor of biochemistry, immunology and microbiology at the University of Ottawa, Faculty of Medicine, University of Ottawa, Canada. Part of the basic course.

Stroke (commonly known as stroke) is one of the three major diseases that seriously endanger human health, and about 5.5 million people die each year from stroke in the world. According to the Ministry of Health CDC 2011 data show that Chinese stroke is rising at nearly 9% per year, it has become China's first cause of death. China is the world's highest cerebrovascular mortality rate (even higher than Europe and the United States 4 times), the World Health Organization (WHO) the latest data show that every 6 seconds there is a stroke in the world, the vast majority of patients So disability, such as hemiplegia, aphasia, blindness and so on. Stroke with high morbidity, high mortality, high recurrence rate and high disability This 'four high' features, has become a serious threat to the health of Chinese residents a major disease. Stroke every year caused by a variety of direct and indirect economic losses of up to tens of billions of dollars, as China's public health and family's huge economic burden. 　　 However, the current stroke treatment, rehabilitation is still a lack of effective treatment. Is a major problem in clinical medicine to be solved. The overall goal of our team's research will focus on the development of new, more clinically relevant compound animal models to explore the molecular mechanisms of death after death, as well as structural and functional recovery of stroke neurons. Through the combination of neurobiology, molecular biology, pharmacology and other means, especially our research group to develop the first mass spectrometry imaging metabolic technology to carry out stroke lipid group study in order to reveal a new neuronal injury signal transduction pathway and Inflammatory regulation of synaptic plasticity of the molecular mechanism for the development of neuroprotective agents and drugs to provide theoretical and practical basis.