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Julio A Aguirre-Ghiso Alberto Toso Yan Xiaojing William G. Finn Afua Mensah Scott A. Armstrong Richard Oscar Francis Jose Javier Bravo Cordero Steven J Burakoff Arek Z. Dudek Balkrishna Jahagirdar Dan J. Schneider Dr. David Saunders Bamlaku Enawgaw Dylan Zylla Muhammad Yasin Tipu Mr. Máté SZILASSY Mr. Roberto MARCOS Mr. Brian CONIBERE Mr. Julio FREYRE View More
Hideo Harigae

Professor
Department of Hematology and Rheumatology
Tohoku University
Japan

Professor Haematology
Biography

Dr. Hideo Harigae, is a Professor of Hematology and Rheumatology , at Tohoku University School of medicine. He is M.D. and Ph.D. His research themes are Pathophysiology of hematological diseases and autoimmune diseases, Development of novel therapies for hematological diseases and autoimmune diseases. Research Keywords for him are erythroid differentiation and iron metabolism, regulatory mechanism of stem cell differentiation, identification and characterization of autoantibody, clarification of pathological characteristics of immune cells in autoimmune diseases , clinical studies of hematological and autoimmune diseases.

Research Intrest

in vitro hematopoietic cell differentiation, generation of model mouse, hematopoietic cell sorting, gene expression analysis

List of Publications
Okabe, M., Unno, M., Harigae, H., Kaku, M., Okitsu, Y., Sasaki, T., ... & Matsuno, S. (2005). Characterization of the organic cation transporter SLC22A16: a doxorubicin importer. Biochemical and biophysical research communications, 333(3), 754-762.
Matsuse, D., Kitada, M., Kohama, M., Nishikawa, K., Makinoshima, H., Wakao, S., ... & Umezawa, A. (2010). Human umbilical cord-derived mesenchymal stromal cells differentiate into functional Schwann cells that sustain peripheral nerve regeneration. Journal of Neuropathology & Experimental Neurology, 69(9), 973-985.
Harigae, H., Takahashi, S., Suwabe, N., Ohtsu, H., Gu, L., Yang, Z., ... & Yamamoto, M. (1998). Differential roles of GATA‐1 and GATA‐2 in growth and differentiation of mast cells. Genes to Cells, 3(1), 39-50.
Nakajima, O., Takahashi, S., Harigae, H., Furuyama, K., Hayashi, N., Sassa, S., & Yamamoto, M. (1999). Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload. The EMBO Journal, 18(22), 6282-6289.
Chen, S., Ishii, N., Ine, S., Ikeda, S., Fujimura, T., Ndhlovu, L. C., ... & Kasai, N. (2005). Regulatory T cell-like activity of Foxp3+ adult T cell leukemia cells. International immunology, 18(2), 269-277.
Yomogida, K., Ohtani, H., Harigae, H., Ito, E., Nishimune, Y., Engel, J. D., & Yamamoto, M. (1994). Developmental stage-and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells. Development, 120(7), 1759-1766.
Experts in Japan
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