George McDonald

Professor
Gastroenterology
Fred Hutchinson Cancer Rearch Center
United States of America

Professor Gastroenterology
Biography

Dr. McDonald graduated from the Washington University School of Medicine in 1967. He works in Seattle, WA and specializes in Gastroenterology. Dr. McDonald is affiliated with Seattle Childrens Hospital and University Of Washington Medical Center. He speaks Chinese ,English , French and Spanish Education & Training MD: Washington University School of Medicine (St. Louis), 1967 Residency: University of Washington, Medicine, 1969 Fellowship: University of Washington, Gastroenterology, 1975 Title Professor of Medicine, Division of Gastroenterology, University of Washington Member, Gastroenterology/Hepatology Section, Clinical Research Division, Fred Hutchinson Cancer Research Center

Research Intrest

Dr. McDonald's research over the last 40 years has been focused on gastrointestinal and hepatobiliary problems in patients with cancer, with an emphasis on complications of and outcomes following hematopoietic cell transplantation. Specific topics have included graft-vs-host disease, sinusoidal obstruction syndrome, viral hepatitis, biliary disease, and infections of the gastrointestinal tract and liver. He formerly directed the Cytokine Analysis Laboratory, a shared resource for investigators at the FHCRC, University of Washington, and Seattle Childrens' Hospital. In collaboration with investigators in the Pharmacology Section, he has examined the pharmacokinetics of chemotherapy drugs used in transplantation, research that has led to methods of limiting toxicity. In 1998, he published a paper describing patients with both leukemia and Crohn’s Disease whose leukemia was cured by bone marrow transplants for leukemia, but whose Crohn’s Disease also disappeared.

List of Publications
Jagasia MH, Greinix HT, Arora M, Williams KM, Wolff D, Cowen EW, Palmer J, Weisdorf D, Treister NS, Cheng G-S et al.. 2015. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group report.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 21(3):389-401.e1
Hingorani SR, Seidel K, Pao E, Lawler R, McDonald GB. 2015. Markers of coagulation activation and acute kidney injury in patients after hematopoietic cell transplantation.. Bone marrow transplantation. 50(5):715-20
Torres HA, Chong PP, DeLima M, Friedman MS, Giralt S, Hammond SP, Kiel PJ, Masur H, McDonald GB, Wingard JR et al.. 2015. Hepatitis C Virus Infection among Hematopoietic Cell Transplant Donors and Recipients: American Society for Blood and Marrow Transplantation Task Force Recommendations.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 21(11):1870-82
Torres HA, McDonald GB. 2016. How I treat hepatitis C virus infection in patients with hematologic malignancies.. Blood. 128(11):1449-1457
Steinbach G, Hockenbery DM, Huls G, Furlong T, Myerson D, Loeb KR, Fann JR, Castilla-Llorente C, McDonald GB, Martin PJ. 2017. Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease.. PloS one. 12(8):e0183284